Tentative Program

Tentative Program – Biology of Acute Respiratory Infection, Ventura, CA March 2012

Sunday PM March 11 – Overview: Host-Pathogen interactions in the lung

Keynote Address – Luke O’Neill – Toll-like receptor and NOD-like receptor signaling in infection and inflammation – School of Biochemistry and Immunology in Trinity College Dublin

Steven Holland – Defects in innate immunity and pneumonia – Laboratory of Clinical Infectious Diseases, NIAID, Bethesda, MD

Peter Openshaw – How RSV causes disease – Director, Centre for Respiratory Infection, National Heart & Lung Institute, Imperial College London

Monday AM 03/12 – Epithelial cell signaling and immunity in lung infection

Jeffrey Whitsett – Regulation of innate immunity by the respiratory epithelium, Chief, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center

Nicholas Lukacs – Respiratory syncytial virus-induced pathogenesis and regulation of pulmonary immune responses – Prof of Pathology, University of Michigan Medical School

Steven Varga – Regulation of the RSV-specific CD8 T cell response – Associate Professor of Microbiology – University of Iowa

Jerry W. Simecka – Pathogenesis of Mycoplasma pneumoniae infection – Prof Dept. Molecular Biology and Immunology,UNT Health Science Center, Fort Worth.

Monday evening – Bacterial infections: genomics/pathogenesis/epidemiology

Tim Foster – S. aureus Interactions with immune signaling – Prof of Microbiology, Trinity College, Dublin.

Binh An Diep – Pathogenesis of S. aureus necrotizing pneumonia – Assistant Adjunct Professor – Department of Medicine, UCSF

Paul Planet – Evolution of the USA300 genome -Assistant Professor of Pediatrics, Columbia University NY

Eric Harvill -Immunopathogenesis of pertussis- Assoc. Prof of Microbiology Infectious Disease – Penn State University

Thomas Clark, MD, MPH – Analysis of current pertussis outbreaks, Epidemiology Team Leader, Meningitis and Vaccine Preventable Diseases Branch, CDC Atlanta GA

Tuesday AM 03/13 – Innate Immunity/ Pneumococcal infection

Bali Pulendran – Dendritic Cell biology in the host response to pneumonia. Professor 
Pathology & Laboratory Medicine, Experimental Pathology
 Emory Vaccine Center

Christopher Karp – Innate immune responses to pulmonary pathogens – Department of Molecular Immunology, Cincinnati Children’s Hospital Research Foundation, Cincinnati, OH.

Stephen Bentley – Viewing short and long range pneumococcal evolution through genome sequencing of different isolate collections – Senior Scientist, Pathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, UK

Richard Malley – Prevention of pneumococcal colonization and disease: A tale of two cells, Division of Infectious Diseases, Children’s Hospital Boston. MA

Shabir Madhi – Challenges and opportunities for preventing pneumococcal pneumonia associated childhood morbidity and mortality – University of the Witwatersrand, Bertsham South Africa

Tuesday Evening – Immunopathogenesis of fungal infection

George Deepe – CCL7-CCL2-CCr2 axis/ IL-4 and fungal immunity – Division of Infectious Diseases, University of Cincinnati College of Medicine

Stuart Levitz – Plasmacytoid dendritic cells in fungal host defenses – Professor of Medicine and Molecular Genetics & Microbiology, University of Massachusetts Medical School, Worcester, MA

Tobias Hohl – Host defense against respiratory fungal infection, Assistant Member, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center Seattle, WA

Marcel Wuethrich – The induction of vaccine-induced anti-fungal T17 cells – University of Wisconsin, Madison, WI.

Wednesday AM 3/14 – Inflammasome/Autophagy/Influenza

Augustine Choi – Crosstalk between autophagy and inflammasomes in innate immunity – Prof of Medicine Harvard Medical School.

Irving Coy Allen – The Role of NLRs During Acute Respiratory Infection – Postdoctoral Research Fellow, University of North Carolina at Chapel Hill.

Adolfo Garcia Sastre – Induction and evasion of innate immunity by influenza viruses, Prof of Microbiology, Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, NY

Daniel Perez -Is there room for the influenza “transmisome”? Associate Professor, Department of Veterinary Medicine, University of Maryland, College Park, MD

Benjamin TenOever – The biology of Influenza A Virus-Generated Small RNAs” Asst. Professor, Mt. Sinai School of Medicine, New York

Wednesday evening – Immune cell recruitment and signaling in bacterial infection

Jay Kolls – “Mucosal Immune requirements for prevention of infection with multi-drug resistant Klebsiella pneumoniae” Professor of Genetics and Pediatrics
 LSU. New Orleans, LA

Paul Kubes – Mechanisms of PMN recruitment – Professor and Director, Calvin, Phoebe and Joan Snyder Institute of Infection, Immunity and Inflammation University of Calgary, Alberta, CA

Theodore J. Standiford – Response of the lung to sepsis, Division of Pulmonary & Critical Care Medicine, University of Michigan Medical Center

Olaf Schneewind – Pneumonic plague – pathogenesis and prevention – Professor 
and Chair of Microbiology, University of Chicago.

Thursday 3/15 AM – Vaccines and Respiratory Viruses

Gary Nabel – “Strategies for the Development of Universal Influenza Vaccines”. Director,
NIH/NIAID/Vaccine Research Center,
Bethesda, MD

Hanna Golding – Expansion of antibody repertoires and affinity maturation following infection or vaccination with influenza viruses – Chief, Lab of Retrovirus Research, FDA.

Ursula Buchholz – “Host response to pneumovirus infection” Staff Scientist, Laboratory of Infectious Diseases, NIAID, NIH

Stephanie Cormier – Why Timing of Initial RSV Infection is Important, Louisiana State University Health Sciences Center

James E. Crowe – The genetic and structural basis for development of human neutralizing antibodies, Prof of Pediatrics, Microbiology and Immunol.
Vanderbilt Program in Vaccine Sciences

Thursday evening- Bacterial/Viral co-infection and the resolution of pneumonia

Jon McCullers — Secondary bacterial infections: the other side of influenza pathogenesis” 
 Associate Member 
Department of Infectious Diseases 
St. Jude Children’s Research Hospital Memphis, TN

Suzanne Dawid -The role of bacterial competition in respiratory tract colonization by Streptococcus pneumoniae.” Assistant Professor ,Microbiology and Immunology, Univ. of Michigan.

Bruce Levy – Lipoxins and resolvins promote the resolution of bacterial pneumonia and ALI. Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital/ Harvard Medical School


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